GABRA4 Antibody
Code | Size | Price |
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PSI-56-576-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Flow Cytometry
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
Gamma-aminobutyric acid receptor subunit alpha-4, GABA(A) receptor subunit alpha-4, GABRA4
Application Note:
For WB starting dilution is: 1:1000
For FACS starting dilution is: 1:10~50
For FACS starting dilution is: 1:10~50
Background:
GABA is the major inhibitory neurotransmitter in the
mammalian brain where it acts at GABA-A receptors, which are
ligand-gated chloride channels. Chloride conductance of these
channels can be modulated by agents such as benzodiazepines that
bind to the GABA-A receptor. At least 16 distinct subunits of
GABA-A receptors have been identified.
Background References:
- Bailey, S.D., et al. Diabetes Care (2010) In press :
- Ruano, G., et al. Pharmacogenomics 11(7):959-971(2010)
- Pinheiro, A.P., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 153B (5), 1070-1080 (2010) :
- Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This GABRA4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 333-361 amino acids from the Central region of human GABRA4.
NCBI Gene ID #:
2557
NCBI Official Name:
Gamma-aminobutyric acid receptor subunit alpha-4
NCBI Official Symbol:
GABRA4
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
62 kDa
Protein Accession #:
P48169
Protein GI Number:
206729865
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience
Swissprot #:
P48169
User NOte:
Optimal dilutions for each application to be determined by the researcher.