KCNC1 Antibody
| Code | Size | Price |
|---|
| PSI-57-805-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Potassium voltage-gated channel subfamily C member 1, NGK2, Voltage-gated potassium channel subunit Kv31, Voltage-gated potassium channel subunit Kv4, KCNC1
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Background:
The Shaker gene family of Drosophila encodes components of
voltage-gated potassium channels and is comprised of four
subfamilies. Based on sequence similarity, this gene is similar to
one of these subfamilies, namely the Shaw subfamily. The protein
encoded by this gene belongs to the delayed rectifier class of
channel proteins and is an integral membrane protein that mediates
the voltage-dependent potassium ion permeability of excitable
membranes. Multiple transcript variants encoding different isoforms
have been inferred for this gene based on orthologous loci.
Background References:
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
- Wang, Z., et al. J. Gen. Physiol. 133(4):361-374(2009)
- Gutman, G.A., et al. Pharmacol. Rev. 57(4):473-508(2005)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This KCNC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 479-508 amino acids from the C-terminal region of human KCNC1.
NCBI Gene ID #:
3746
NCBI Official Name:
Potassium voltage-gated channel subfamily C member 1
NCBI Official Symbol:
KCNC1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
58 kDa
Protein Accession #:
P48547
Protein GI Number:
1352085
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience
Swissprot #:
P48547
User NOte:
Optimal dilutions for each application to be determined by the researcher.