SPRN Antibody

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ProSci
Product Code: PSI-61-650
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-61-650-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis of lysate from human brain tissue lysate, using SPRN Antibody at 1:1000 at each lane.
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SPRN Antibody IHC analysis in formalin fixed and paraffin embedded brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.
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Western blot analysis of lysate from human brain tissue lysate, using SPRN Antibody at 1:1000 at each lane.
SPRN Antibody IHC analysis in formalin fixed and paraffin embedded brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

Documents

Further Information

Additional Names:
Shadow of prion protein, Protein shadoo, SPRN, SHO
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100
Background:
SPRN has PrP(C)-like neuroprotective activity. SPRN may act as a modulator for the biological actions of normal and abnormal PrP.
Background References:
  • Beck, J.A., et al. J. Med. Genet. 45(12):813-817(2008)
  • Van den Brulle, J., et al. BioTechniques 45(3):340-343(2008)
  • Premzl, M., et al. Mol. Biol. Evol. 21(12):2210-2231(2004)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This SPRN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 76-105 amino acids from the C-terminal region of human SPRN.
NCBI Gene ID #:
503542
NCBI Official Name:
Shadow of prion protein
NCBI Official Symbol:
SPRN
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
15 kDa
Protein Accession #:
Q5BIV9
Protein GI Number:
74722519
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience
Swissprot #:
Q5BIV9
User NOte:
Optimal dilutions for each application to be determined by the researcher.