ELAVL3 Antibody

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ProSci
Product Code: PSI-56-996
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-56-996-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis of lysate from human brain tissue lysate, using ELAVL3 Antibody at 1:1000 at each lane.
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Western blot analysis of lysate from human brain tissue lysate, using ELAVL3 Antibody at 1:1000 at each lane.
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Western blot analysis of lysate from human brain tissue lysate, using ELAVL3 Antibody at 1:1000 at each lane.
Western blot analysis of lysate from human brain tissue lysate, using ELAVL3 Antibody at 1:1000 at each lane.

Documents

Further Information

Additional Names:
ELAV-like protein 3, Hu-antigen C, HuC, Paraneoplastic cerebellar degeneration-associated antigen, Paraneoplastic limbic encephalitis antigen 21, ELAVL3, HUC, PLE21
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50
Background:
A member of the ELAVL protein family, ELAV-like 3 is a neural-specific RNA-binding protein which contains three RNP-type RNA recognition motifs. The observation that ELAVL3 is one of several Hu antigens (neuronal-specific RNA-binding proteins) recognized by the anti-Hu serum antibody present in sera from patients with paraneoplastic encephalomyelitis and sensory neuronopathy (PEM/PSN) suggests it has a role in neurogenesis. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Background References:
  • Behrends, U., et al. Int. J. Cancer 100(6):669-677(2002)
  • Park, S., et al. Mol. Cell. Biol. 20(13):4765-4772(2000)
  • King, P.H. Nucleic Acids Res. 28 (7), E20 (2000) :
  • Sakai, K., et al. Biochem. Biophys. Res. Commun. 256(2):263-268(1999)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This ELAVL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 71-99 amino acids from the N-terminal region of human ELAVL3.
NCBI Gene ID #:
1995
NCBI Official Name:
ELAV-like protein 3
NCBI Official Symbol:
ELAVL3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
40 kDa
Protein Accession #:
Q14576
Protein GI Number:
21264436
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience
Swissprot #:
Q14576
User NOte:
Optimal dilutions for each application to be determined by the researcher.