CNTNAP2 Antibody

ProSci
Product Code: PSI-63-599
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-63-599-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis of CNTNAP2 Antibody in CEM cell line lysates (35ug/lane)
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Formalin-fixed and paraffin-embedded mouse brain tissue reacted with CNTNAP2 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.

Western blot analysis of CNTNAP2 Antibody in CEM cell line lysates (35ug/lane)
Formalin-fixed and paraffin-embedded mouse brain tissue reacted with CNTNAP2 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.

Further Information

Additional Names:
Contactin-associated protein-like 2, Cell recognition molecule Caspr2, CNTNAP2, CASPR2 {ECO:0000303|PubMed:10624965}, KIAA0868
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100
Background:
CNTNAP2 is a member of the neurexin family which functions in the vertebrate nervous system as cell adhesion molecules and receptors. This protein, like other neurexin proteins, contains epidermal growth factor repeats and laminin G domains. In addition, it includes an F5/8 type C omain,discoidin/neuropilin- and fibrinogen-like domains, thrombospondin N-terminal-like domains and a putative PDZ binding site. This protein is localized at the juxtaparanodes of myelinated axons, and mediates interactions between neurons and glia during nervous system development and is also involved in localization of potassium channels within differentiating axons.
Background References:
  • Denisenko-Nehrbass,N., et.al., Eur. J. Neurosci. 17 (2), 411-416 (2003)
  • Nakayama,M., et.al., Genome Res. 12 (11), 1773-1784 (2002)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This CNTNAP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1079-1106 amino acids from the Central region of human CNTNAP2.
NCBI Gene ID #:
26047
NCBI Official Name:
Contactin-associated protein-like 2
NCBI Official Symbol:
CNTNAP2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
148 kDa
Protein Accession #:
Q9UHC6
Protein GI Number:
17433089
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience
Swissprot #:
Q9UHC6
User NOte:
Optimal dilutions for each application to be determined by the researcher.