CALCA Antibody
| Code | Size | Price |
|---|
| PSI-55-645-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Calcitonin gene-related peptide 1, Alpha-type CGRP, Calcitonin gene-related peptide I, CGRP-I, CALCA, CALC1
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100
For IHC-P starting dilution is: 1:50~100
Background:
This gene encodes the peptide hormones calcitonin,
calcitonin gene-related peptide and katacalcin by tissue-specific
alternative RNA splicing of the gene transcripts and cleavage of
inactive precursor proteins. Calcitonin is involved in calcium
regulation and acts to regulate phosphorus metabolism. Calcitonin
gene-related peptide functions as a vasodilator while katacalcin is
a calcium-lowering peptide. Multiple transcript variants encoding
different isoforms have been found for this gene.
Background References:
- Giroux, S., et al. Bone 47(5):975-981(2010)
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Lee, J.Y., et al. KoreanLab Med 30(4):406-413(2010)
- Giovanella, L., et al. Clin. Chem. Lab. Med. 48(8):1163-1165(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This CALCA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 56-83 amino acids from the Central region of human CALCA.
NCBI Gene ID #:
796
NCBI Official Name:
Calcitonin gene-related peptide 1
NCBI Official Symbol:
CALCA
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
14 kDa
Protein Accession #:
P06881
Protein GI Number:
308153625
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience
Swissprot #:
P06881
User NOte:
Optimal dilutions for each application to be determined by the researcher.