TAC3 Antibody
| Code | Size | Price |
|---|
| PSI-57-679-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Tachykinin-3, ZNEUROK1, Neurokinin-B, NKB, Neuromedin-K, TAC3, NKNB
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Background:
This gene encodes a member of the tachykinin family of
secreted neuropeptides. The encoded protein is primarily expressed
in the central and peripheral nervous system and functions as a
neurotransmitter. This protein is the ligand for the neurokinin-3
receptor. This protein is also expressed in the outer
syncytiotrophoblast of the placenta and may be associated with
pregnancy-induced hypertension and pre-eclampsia. Mutations in this
gene are associated with normosmic hypogonadotropic hypogonadism.
Alternate splicing results in multiple transcript variants.
Background References:
- Klassert, T.E., et al. J. Neuroimmunol. 227 (1-2), 202-207 (2010) :
- Hrabovszky, E., et al. Eur. J. Neurosci. 31(11):1984-1998(2010)
- Gianetti, E., et al. J. Clin. Endocrinol. Metab. 95(6):2857-2867(2010)
- Young, J., et al. J. Clin. Endocrinol. Metab. 95(5):2287-2295(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This TAC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 54-83 amino acids from the Central region of human TAC3.
NCBI Gene ID #:
6866
NCBI Official Name:
Tachykinin-3
NCBI Official Symbol:
TAC3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
13 kDa
Protein Accession #:
Q9UHF0
Protein GI Number:
18203501
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience
Swissprot #:
Q9UHF0
User NOte:
Optimal dilutions for each application to be determined by the researcher.