P2RX5 Antibody

ProSci
Product Code: PSI-57-451
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-57-451-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in K562 cell line lysates (35ug/lane).
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P2RX5 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human cervix tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

Western blot analysis in K562 cell line lysates (35ug/lane).
P2RX5 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human cervix tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

Further Information

Additional Names:
P2X purinoceptor 5, P2X5, ATP receptor, Purinergic receptor, P2RX5, P2X5
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50
Background:
The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel. Several characteristic motifs of ATP-gated channels are present in its primary structure, but, unlike other members of the purinoceptors family, this receptor has only a single transmembrane domain. Three transcript variants encoding distinct isoforms have been identified for this gene.
Background References:
  • Kotnis, S., et al. Mol. Pharmacol. 77(6):953-960(2010)
  • Overes, I.M., et al. Cancer Immunol. Immunother. 58(3):429-439(2009)
  • Dubyak, G.R. Mol. Pharmacol. 72(6):1402-1405(2007)
  • Lamesch, P., et al. Genomics 89(3):307-315(2007)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This P2RX5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 325-353 amino acids from the C-terminal region of human P2RX5.
NCBI Gene ID #:
5026
NCBI Official Name:
P2X purinoceptor 5
NCBI Official Symbol:
P2RX5
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
47 kDa
Protein Accession #:
Q93086
Protein GI Number:
209572778
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience
Swissprot #:
Q93086
User NOte:
Optimal dilutions for each application to be determined by the researcher.