PNOC Antibody

Contact us
ProSci
Product Code: PSI-63-889
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-63-889-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

1 / 3
Western Blot at 1:4000 dilution Lane 1: human brain lysate Lane 2: HepG2 whole cell lysate Lane 3: HL-60 whole cell lysate Lysates/proteins at 20 ug per lane.
2 / 3
Western blot analysis of PNOC Antibody in HepG2 cell line lysates (35ug/lane)
3 / 3
❮❯

Western Blot at 1:4000 dilution Lane 1: human brain lysate Lane 2: HepG2 whole cell lysate Lane 3: HL-60 whole cell lysate Lysates/proteins at 20 ug per lane.
Western blot analysis of PNOC Antibody in HepG2 cell line lysates (35ug/lane)

Documents

Further Information

Additional Names:
Prepronociceptin, Neuropeptide 1, Nociceptin, Orphanin FQ, PPNOC, Neuropeptide 2, PNOC, OFQ
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100
Background:
PNOC is the ligand of the opioid receptor-like receptor (OPRL1). It may act as a transmitter in the brain by modulating nociceptive and locomotor behavior. This protein may be involved in neuronal differentiation and development
Background References:
  • Kuzmin,A., et.al., Brain Res. 1305 SUPPL, S80-S85 (2009)
  • Rocha,L., et.al., Neurobiol. Dis. 35 (3), 466-473 (2009)
  • de Krom,M., et.al., Biol. Psychiatry 65 (7), 625-630 (2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat
Immunogen:
This PNOC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 126-151 amino acids from the Central region of human PNOC.
NCBI Gene ID #:
5368
NCBI Official Name:
Prepronociceptin
NCBI Official Symbol:
PNOC
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
20 kDa
Protein Accession #:
Q13519
Protein GI Number:
2494348
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience
Swissprot #:
Q13519
User NOte:
Optimal dilutions for each application to be determined by the researcher.