DFNB31 Antibody
| Code | Size | Price |
|---|
| PSI-55-639-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Whirlin, Autosomal recessive deafness type 31 protein, DFNB31, KIAA1526, WHRN
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Background:
This gene is thought to function in the organization and
stabilization of sterocilia elongation and actin cystoskeletal
assembly, based on studies of the related mouse gene. Mutations in
this gene have been associated with autosomal recessive
non-syndromic deafness and Usher Syndrome. Alternative splicing of
this gene results in multiple transcript variants encoding
different isoforms.
Background References:
- Letra, A., et al. Am. J. Med. Genet.152A (7), 1701-1710 (2010) :
- Secolin, R., et al. Psychiatr. Genet. 20(3):126-129(2010)
- Aller, E., et al. Mol. Vis. 16, 495-500 (2010) :
- Toiyama, Y., et al. Int. J. Oncol. 35(4):709-715(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This DFNB31 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 378-406 amino acids from the Central region of human DFNB31.
NCBI Gene ID #:
25861
NCBI Official Name:
Whirlin
NCBI Official Symbol:
DFNB31
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
97 kDa
Protein Accession #:
Q9P202
Protein GI Number:
296453079
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience
Swissprot #:
Q9P202
User NOte:
Optimal dilutions for each application to be determined by the researcher.