SLC12A6 Antibody
| Code | Size | Price |
|---|
| PSI-56-387-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Solute carrier family 12 member 6, Electroneutral potassium-chloride cotransporter 3, K-Cl cotransporter 3, SLC12A6, KCC3
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Background:
This gene is a member of the K-Cl cotransporter (KCC)
family. K-Cl cotransporters are integral membrane proteins that
lower intracellular chloride concentrations below the
electrochemical equilibrium potential. The proteins encoded by this
gene are activated by cell swelling induced by hypotonic
conditions. Alternate splicing results in multiple transcript
variants encoding different isoforms. Mutations in this gene are
associated with agenesis of the corpus callosum with peripheral
neuropathy.
Background References:
- Rinehart, J., et al. Cell 138(3):525-536(2009)
- Rudnik-Schoneborn, S., et al. Neuropediatrics 40(3):129-133(2009)
- de Krom, M., et al. Biol. Psychiatry 65(7):625-630(2009)
- Moser, D., et al. Neuropsychopharmacology 34(2):458-467(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This SLC12A6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 13-42 amino acids from the N-terminal region of human SLC12A6.
NCBI Gene ID #:
9990
NCBI Official Name:
Solute carrier family 12 member 6
NCBI Official Symbol:
SLC12A6
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
128 kDa
Protein Accession #:
Q9UHW9
Protein GI Number:
27151690
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience
Swissprot #:
Q9UHW9
User NOte:
Optimal dilutions for each application to be determined by the researcher.