KCNV2 Antibody
| Code | Size | Price |
|---|
| PSI-56-841-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Potassium voltage-gated channel subfamily V member 2, Voltage-gated potassium channel subunit Kv82, KCNV2
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Background:
Voltage-gated potassium (Kv) channels represent the most
complex class of voltage-gated ion channels from both functional
and structural standpoints. Their diverse functions include
regulating neurotransmitter release, heart rate, insulin secretion,
neuronal excitability, epithelial electrolyte transport, smooth
muscle contraction, and cell volume. This gene encodes a member of
the potassium voltage-gated channel subfamily V. This member is
identified as a 'silent subunit', and it does not form
homomultimers, but forms heteromultimers with several other
subfamily members. Through obligatory heteromerization, it exerts a
function-altering effect on other potassium channel subunits. This
protein is strongly expressed in pancreas and has a weaker
expression in several other tissues.
Background References:
- Robson, A.G., et al. Retina (Philadelphia, Pa.) 30(1):51-62(2010)
- Ben Salah, S., et al. Am. J. Ophthalmol. 145(6):1099-1106(2008)
- Wissinger, B., et al. Invest. Ophthalmol. Vis. Sci. 49(2):751-757(2008)
- Thiagalingam, S., et al. Ophthalmic Genet. 28(3):135-142(2007)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This KCNV2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 478-507 amino acids from the C-terminal region of human KCNV2.
NCBI Gene ID #:
169522
NCBI Official Name:
Potassium voltage-gated channel subfamily V member 2
NCBI Official Symbol:
KCNV2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
62 kDa
Protein Accession #:
Q8TDN2
Protein GI Number:
26006804
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience
Swissprot #:
Q8TDN2
User NOte:
Optimal dilutions for each application to be determined by the researcher.