RCAN3 Antibody

ProSci
Product Code: PSI-57-705
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-57-705-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

1 / 2
Western blot analysis in K562 cell line lysates (35ug/lane).
2 / 2
RCAN3 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

Western blot analysis in K562 cell line lysates (35ug/lane).
RCAN3 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

Further Information

Additional Names:
Calcipressin-3, Down syndrome candidate region 1-like protein 2, Myocyte-enriched calcineurin-interacting protein 3, MCIP3, Regulator of calcineurin 3, RCAN3, DSCR1L2
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50
Background:
RCAN3 inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Could play a role during central nervous system development (By similarity).
Background References:
  • Sales, K.J., et al. Biochim. Biophys. Acta 1793(12):1917-1928(2009)
  • Enjuanes, A., et al. Cancer Res. 68(24):10178-10186(2008)
  • Facchin, F., et al. Gene 407 (1-2), 159-168 (2008) :
  • Mulero, M.C., et al. Biochim. Biophys. Acta 1773(3):330-341(2007)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This RCAN3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 194-222 amino acids from the C-terminal region of human RCAN3.
NCBI Gene ID #:
11123
NCBI Official Name:
Calcipressin-3
NCBI Official Symbol:
RCAN3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
27 kDa
Protein Accession #:
Q9UKA8
Protein GI Number:
15213951
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience
Swissprot #:
Q9UKA8
User NOte:
Optimal dilutions for each application to be determined by the researcher.