BEAN Antibody
| Code | Size | Price |
|---|
| PSI-57-024-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Protein BEAN1, Brain-expressed protein associating with Nedd4 homolog, BEAN, BEAN1
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Background:
The protein encoded by this gene is one of several
proteins that interact with NEDD4, a member of a family of
ubiquitin-protein ligases. These proteins have PY motifs in common
that bind to the WW domains of NEDD4. NEDD4 is developmentally
regulated, and is highly expressed in embryonic tissues. Mutations
in this gene (i.e., intronic insertions of >100 copies of
pentanucleotide repeats including a (TGGAA)n sequence) are
associated with spinocerebellar ataxia type 31. Alternatively
spliced transcript variants encoding different isoforms have been
found for this gene.
Background References:
- Sato, N., et al. Am. J. Hum. Genet. 85(5):544-557(2009)
- Jolliffe, C.N., et al. Biochem. J. 351 PT 3, 557-565 (2000) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This BEAN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 45-73 amino acids from the N-terminal region of human BEAN.
NCBI Gene ID #:
146227
NCBI Official Name:
Protein BEAN1
NCBI Official Symbol:
BEAN1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
29 kDa
Protein Accession #:
Q3B7T3
Protein GI Number:
190360694
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience
Swissprot #:
Q3B7T3
User NOte:
Optimal dilutions for each application to be determined by the researcher.