GRIN3B Antibody

ProSci
Product Code: PSI-56-326
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-56-326-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in A549 cell line lysates (35ug/lane).
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GRIN3B Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

Western blot analysis in A549 cell line lysates (35ug/lane).
GRIN3B Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

Further Information

Additional Names:
Glutamate receptor ionotropic, NMDA 3B, GluN3B, N-methyl-D-aspartate receptor subtype 3B, NMDAR3B, NR3B, GRIN3B
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50
Background:
GRIN3B is a NMDA receptor subtype of glutamate-gated ion channels with reduced single-channel conductance, low calcium permeability and low voltage-dependent sensitivity to magnesium. It is mediated by glycine.
Background References:
  • Sedaghati, M., et al. Eur. J. Pharmacol. 633 (1-3), 50-54 (2010) :
  • Saus, E., et al.Psychiatr Res (2010) In press :
  • Need, A.C., et al. Eur. J. Hum. Genet. 17(7):946-957(2009)
  • Liu, H.P., et al. Dement Geriatr Cogn Disord 28(6):521-527(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This GRIN3B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 904-933 amino acids from the C-terminal region of human GRIN3B.
NCBI Gene ID #:
116444
NCBI Official Name:
Glutamate receptor ionotropic, NMDA 3B
NCBI Official Symbol:
GRIN3B
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
113 kDa
Protein Accession #:
O60391
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience
Swissprot #:
O60391
User NOte:
Optimal dilutions for each application to be determined by the researcher.