APCS Antibody
| Code | Size | Price |
|---|
| PSI-55-331-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Serum amyloid P-component, SAP, 95S alpha-1-glycoprotein, Serum amyloid P-component(1-203), APCS, PTX2
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100
For IHC-P starting dilution is: 1:50~100
Background:
The protein encoded by this gene is a glycoprotein,
belonging to the pentraxin family of proteins, which has a
characteristic pentameric organization. These family members have
considerable sequence homology which is thought to be the result of
gene duplication. The binding of the encoded protein to proteins in
the pathological amyloid cross-beta fold suggests its possible role
as a chaperone. This protein is also thought to control the
degradation of chromatin. It has been demonstrated that this
protein binds to apoptotic cells at an early stage, which raises
the possibility that it is involved in dealing with apoptotic cells
in vivo.
Background References:
- Song, Z., et al. Atherosclerosis 211(1):90-95(2010)
- Davila, S., et al. Genes Immun. 11(3):232-238(2010)
- McGeachie, M., et al. Circulation 120(24):2448-2454(2009)
- Lu, J., et al. Nature 456(7224):989-992(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This APCS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 151-178 amino acids from the C-terminal region of human APCS.
NCBI Gene ID #:
325
NCBI Official Name:
Serum amyloid P-component
NCBI Official Symbol:
APCS
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
25 kDa
Protein Accession #:
P02743
Protein GI Number:
730704
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience
Swissprot #:
P02743
User NOte:
Optimal dilutions for each application to be determined by the researcher.