SYN3 Antibody
| Code | Size | Price |
|---|
| PSI-62-038-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Synapsin-3, Synapsin III, SYN3
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100
For IHC-P starting dilution is: 1:50~100
Background:
This gene is a member of the synapsin gene family.
Synapsins encode neuronal phosphoproteins which associate with the
cytoplasmic surface of synaptic vesicles. Family members are
characterized by common protein domains, and they are implicated in
synaptogenesis and the modulation of neurotransmitter release,
suggesting a potential role in several neuropsychiatric diseases.
The protein encoded by this gene shares the synapsin family domain
model, with domains A, C, and E exhibiting the highest degree of
conservation. The protein contains a unique domain J, located
between domains C and E. Based on this gene's localization to
22q12.3, a possible schizophrenia susceptibility locus, and the
established neurobiological roles of the synapsins, this family
member may represent a candidate gene for schizophrenia. The TIMP3
gene is located within an intron of this gene and is transcribed in
the opposite direction.
Background References:
- Tsai, M.T., et al. Am. J. Med. Genet. 114(1):79-83(2002)
- Kao, H.T., et al. J. Exp. Zool. 285(4):360-377(1999)
- Porton, B., et al. J. Neurochem. 73(6):2266-2271(1999)
- Kao, H.T., et al. Proc. Natl. Acad. Sci. U.S.A. 95(8):4667-4672(1998)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This SYN3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 363-388 amino acids from the Central region of human SYN3.
NCBI Gene ID #:
8224
NCBI Official Name:
Synapsin-3
NCBI Official Symbol:
SYN3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
63 kDa
Protein Accession #:
O14994
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience
Swissprot #:
O14994
User NOte:
Optimal dilutions for each application to be determined by the researcher.