GABRD Antibody
| Code | Size | Price |
|---|
| PSI-63-881-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Fluorescence-activated cell sorting (FACS)
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Gamma-aminobutyric acid receptor subunit delta, GABA(A) receptor subunit delta, GABRD
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100
For FACS starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:50~100
For FACS starting dilution is: 1:10~50
Background:
GABRD is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. The GABA-A receptor is generally pentameric and there are five types of subunits: alpha, beta, gamma, delta, and rho. This protein encodes the delta subunit.
Background References:
- Gratacos,M., et.al., Am. J. Med. Genet.Neuropsychiatr. Genet. 150B (6), 808-816 (2009)
- Maldonado-Aviles,J.G., et.al., AmPsychiatry 166 (4), 450-459 (2009)
- Tabakoff,B., et.al., BMC Biol. 7, 70 (2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This GABRD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 331-358 amino acids from the Central region of human GABRD.
NCBI Gene ID #:
2563
NCBI Official Name:
Gamma-aminobutyric acid receptor subunit delta
NCBI Official Symbol:
GABRD
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
51 kDa
Protein Accession #:
O14764
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience
Swissprot #:
O14764
User NOte:
Optimal dilutions for each application to be determined by the researcher.