CHRM2 Antibody
| Code | Size | Price |
|---|
| PSI-57-722-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Muscarinic acetylcholine receptor M2, CHRM2
Application Note:
For WB starting dilution is: 1:1000
Background:
The muscarinic cholinergic receptors belong to a larger
family of G protein-coupled receptors. The functional diversity of
these receptors is defined by the binding of acetylcholine to these
receptors and includes cellular responses such as adenylate cyclase
inhibition, phosphoinositide degeneration, and potassium channel
mediation. Muscarinic receptors influence many effects of
acetylcholine in the central and peripheral nervous system. The
muscarinic cholinergic receptor 2 is involved in mediation of
bradycardia and a decrease in cardiac contractility. Multiple
alternatively spliced transcript variants have been described for
this gene.
Background References:
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Ruano, G., et al. Pharmacogenomics 11(7):959-971(2010)
- Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
- Cannon, D.M., et al. Mol. Psychiatry (2010) In press :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Pig, Rat
Immunogen:
This CHRM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 336-364 amino acids from the Central region of human CHRM2.
NCBI Gene ID #:
1129
NCBI Official Name:
Muscarinic acetylcholine receptor M2
NCBI Official Symbol:
CHRM2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
52 kDa
Protein Accession #:
P08172
Protein GI Number:
113122
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience,Growth Factor
Swissprot #:
P08172
User NOte:
Optimal dilutions for each application to be determined by the researcher.