OPRK1 Antibody

ProSci
Product Code: PSI-60-943
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-60-943-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in MDA-MB453 cell line lysates (35ug/lane).

Western blot analysis in MDA-MB453 cell line lysates (35ug/lane).

Further Information

Additional Names:
Kappa-type opioid receptor, K-OR-1, KOR-1, OPRK1, OPRK
Application Note:
For WB starting dilution is: 1:1000
Background:
Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Receptor for dynorphins. May play a role in arousal and regulation of autonomic and neuroendocrine functions.
Background References:
  • Pinheiro, A.P., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 153B (5), 1070-1080 (2010) :
  • Bruijnzeel, A.W. Brain Res Rev 62(1):127-146(2009)
  • Gratacos, M., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 150B (6), 808-816 (2009) :
  • de Krom, M., et al. Biol. Psychiatry 65(7):625-630(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Immunogen:
This OPRK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 181-209 amino acids from the Central region of human OPRK1.
NCBI Gene ID #:
4986
NCBI Official Name:
Kappa-type opioid receptor
NCBI Official Symbol:
OPRK1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
43 kDa
Protein Accession #:
P41145
Protein GI Number:
116242691
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience,Growth Factor
Swissprot #:
P41145
User NOte:
Optimal dilutions for each application to be determined by the researcher.