CYSLTR1 Antibody
| Code | Size | Price |
|---|
| PSI-58-011-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Cysteinyl leukotriene receptor 1, CysLTR1, Cysteinyl leukotriene D4 receptor, LTD4 receptor, G-protein coupled receptor HG55, HMTMF81, CYSLTR1, CYSLT1
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Background:
The cysteinyl leukotrienes LTC4, LTD4, and LTE4 are
important mediators of human bronchial asthma. Pharmacologic
studies have determined that cysteinyl leukotrienes activate at
least 2 receptors, the protein encoded by this gene and CYSLTR2.
This encoded receptor is a member of the superfamily of G
protein-coupled receptors. Activation of this receptor by LTD4
results in contraction and proliferation of smooth muscle, oedema,
eosinophil migration and damage to the mucus layer in the lung.
Background References:
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Boulay, M.E., et al. Prostaglandins Leukot. Essent. Fatty Acids 83(1):15-22(2010)
- Schuurhof, A., et al. Pediatr. Pulmonol. 45(6):608-613(2010)
- Hasegawa, S., et al. Platelets 21(4):253-259(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This CYSLTR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 144-172 amino acids from the Central region of human CYSLTR1.
NCBI Gene ID #:
10800
NCBI Official Name:
Cysteinyl leukotriene receptor 1
NCBI Official Symbol:
CYSLTR1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
39 kDa
Protein Accession #:
Q9Y271
Protein GI Number:
20138087
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience,Growth Factor
Swissprot #:
Q9Y271
User NOte:
Optimal dilutions for each application to be determined by the researcher.