CB2 Antibody
| Code | Size | Price |
|---|
| PSI-55-328-400ul | 400ul | £662.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Fluorescence-activated cell sorting (FACS)
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Cannabinoid receptor 2, CB-2, CB2, hCB2, CX5, CNR2, CB2A, CB2B
Application Note:
For IHC-P starting dilution is: 1:10~50
For FACS starting dilution is: 1:25
For WB starting dilution is: 1:1000
For FACS starting dilution is: 1:25
For WB starting dilution is: 1:1000
Background:
The cannabinoid delta-9-tetrahydrocannabinol is the
principal psychoactive ingredient of marijuana. The proteins
encoded by this gene and the cannabinoid receptor 1 (brain) (CNR1)
gene have the characteristics of a guanine nucleotide-binding
protein (G-protein)-coupled receptor for cannabinoids. They inhibit
adenylate cyclase activity in a dose-dependent, stereoselective,
and pertussis toxin-sensitive manner. These proteins have been
found to be involved in the cannabinoid-induced CNS effects
(including alterations in mood and cognition) experienced by users
of marijuana. The cannabinoid receptors are members of family 1 of
the G-protein-coupled receptors.
Background References:
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Larrinaga, G., et al. Histol. Histopathol. 25(9):1133-1138(2010)
- Pinheiro, A.P., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 153B (5), 1070-1080 (2010) :
- Taylor, A.H., et al. Histochem. Cell Biol. 133(5):557-565(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This CB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 329-356 amino acids from the C-terminal region of human CB2.
NCBI Gene ID #:
1269
NCBI Official Name:
Cannabinoid receptor 2
NCBI Official Symbol:
CNR2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
40 kDa
Protein Accession #:
P34972
Protein GI Number:
461697
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience,Growth Factor
Swissprot #:
P34972
User NOte:
Optimal dilutions for each application to be determined by the researcher.