PPP2R5C Antibody

ProSci
Product Code: PSI-57-430
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-57-430-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in MDA-MB231 cell line lysates (35ug/lane).

Western blot analysis in MDA-MB231 cell line lysates (35ug/lane).

Further Information

Additional Names:
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform, PP2A B subunit isoform B'-gamma, PP2A B subunit isoform B56-gamma, PP2A B subunit isoform PR61-gamma, PP2A B subunit isoform R5-gamma, Renal carcinoma antigen NY-REN-29, PPP2R5C, KIAA0044
Application Note:
For WB starting dilution is: 1:1000
Background:
The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a gamma isoform of the regulatory subunit B56 subfamily. Alternatively spliced transcript variants encoding different isoforms have been identified.
Background References:
  • Anney, R., et al. Hum. Mol. Genet. 19(20):4072-4082(2010)
  • Lee, T.Y., et al. J. Biol. Chem. 285(28):21567-21580(2010)
  • Shouse, G.P., et al. Oncogene 29(27):3933-3941(2010)
  • Tung, H.Y., et al. FEBS Lett. 401 (2-3), 197-201 (1997) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This PPP2R5C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 465-494 amino acids from the C-terminal region of human PPP2R5C.
NCBI Gene ID #:
5527
NCBI Official Name:
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform
NCBI Official Symbol:
PPP2R5C
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
61 kDa
Protein Accession #:
Q13362
Protein GI Number:
116241235
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience,Signal Transduction
Swissprot #:
Q13362
User NOte:
Optimal dilutions for each application to be determined by the researcher.