PPFIA1 Antibody
| Code | Size | Price |
|---|
| PSI-59-192-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Liprin-alpha-1, LAR-interacting protein 1, LIP-1, Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1, PTPRF-interacting protein alpha-1, PPFIA1, LIP1
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene is a member of the LAR
protein-tyrosine phosphatase-interacting protein (liprin) family.
Liprins interact with members of LAR family of transmembrane
protein tyrosine phosphatases, which are known to be important for
axon guidance and mammary gland development. This protein binds to
the intracellular membrane-distal phosphatase domain of tyrosine
phosphatase LAR, and appears to localize LAR to cell focal
adhesions. This interaction may regulate the disassembly of focal
adhesion and thus help orchestrate cell-matrix interactions.
Alternatively spliced transcript variants encoding distinct
isoforms have been described.
Background References:
- Asperti, C., et al. Exp. Cell Res. 316(6):915-926(2010)
- Dancau, A.M., et al. Genes Chromosomes Cancer 49(1):1-8(2010)
- Asperti, C., et al. J. Cell. Sci. 122 (PT 18), 3225-3232 (2009) :
- Venkatesan, K., et al. Nat. Methods 6(1):83-90(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This PPFIA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 52-80 amino acids from the N-terminal region of human PPFIA1.
NCBI Gene ID #:
8500
NCBI Official Name:
Liprin-alpha-1
NCBI Official Symbol:
PPFIA1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
136 kDa
Protein Accession #:
Q13136
Protein GI Number:
42558969
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience,Signal Transduction
Swissprot #:
Q13136
User NOte:
Optimal dilutions for each application to be determined by the researcher.