KCNMB1 Antibody

ProSci
Product Code: PSI-57-957
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-57-957-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in A549 cell line lysates (35ug/lane).

Western blot analysis in A549 cell line lysates (35ug/lane).

Further Information

Additional Names:
Calcium-activated potassium channel subunit beta-1, BK channel subunit beta-1, BKbeta, BKbeta1, Hbeta1, Calcium-activated potassium channel, subfamily M subunit beta-1, Calcium-activated potassium channel subunit beta, Charybdotoxin receptor subunit beta-1, K(VCA)beta-1, Maxi K channel subunit beta-1, Slo-beta-1, Slo-beta, KCNMB1
Application Note:
For WB starting dilution is: 1:1000
Background:
MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the product of this gene, the modulatory beta subunit. Intracellular calcium regulates the physical association between the alpha and beta subunits.
Background References:
  • Bailey, S.D., et al. Diabetes Care (2010) In press :
  • Xie, M.J., et al. Am. J. Physiol., Cell Physiol. 298 (6), C1489-C1500 (2010) :
  • Yokoyama, K., et al. Nephron Clin Pract 115 (4), C237-C243 (2010) :
  • Long, X., et al. J. Biol. Chem. 284(48):33671-33682(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This KCNMB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 43-72 amino acids from the Central region of human KCNMB1.
NCBI Gene ID #:
3779
NCBI Official Name:
Calcium-activated potassium channel subunit beta-1
NCBI Official Symbol:
KCNMB1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
22 kDa
Protein Accession #:
Q16558
Protein GI Number:
292495100
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience,Signal Transduction
Swissprot #:
Q16558
User NOte:
Optimal dilutions for each application to be determined by the researcher.