PDE7B Antibody

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ProSci
Product Code: PSI-55-329
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-55-329-400ul400ul£626.00
Quantity:
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Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in ZR-75-1 cell line lysates (35ug/lane).
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Western blot analysis in ZR-75-1 cell line lysates (35ug/lane).

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Further Information

Additional Names:
cAMP-specific 3',5'-cyclic phosphodiesterase 7B, PDE7B
Application Note:
For WB starting dilution is: 1:1000
Background:
The 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a cAMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family.
Background References:
  • Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
  • Kestenbaum, B., et al. J. Am. Soc. Nephrol. 21(7):1223-1232(2010)
  • Joslyn, G., et al. Alcohol. Clin. Exp. Res. 34(5):800-812(2010)
  • Ikeda, M., et al. Biol. Psychiatry 67(3):263-269(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This PDE7B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 421-450 amino acids from the C-terminal region of human PDE7B.
NCBI Gene ID #:
27115
NCBI Official Name:
cAMP-specific 3',5'-cyclic phosphodiesterase 7B
NCBI Official Symbol:
PDE7B
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
52 kDa
Protein Accession #:
Q9NP56
Protein GI Number:
13626185
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience,Signal Transduction
Swissprot #:
Q9NP56
User NOte:
Optimal dilutions for each application to be determined by the researcher.