RLN2 Antibody
| Code | Size | Price |
|---|
| PSI-60-368-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Prorelaxin H2, Relaxin B chain, Relaxin A chain, RLN2
Application Note:
For WB starting dilution is: 1:1000
Background:
Relaxins are known endocrine and autocrine/paracrine
hormones, belonging to the insulin gene superfamily. In the human
there are three non-allelic relaxin genes, RLN1, RLN2 and RLN3.
RLN1 and RLN2 share high sequence homology. The active form of the
encoded protein consists of an A chain and a B chain but their
cleavage sites are not definitely described yet. Relaxin is
produced by the ovary, and targets the mammalian reproductive
system to ripen the cervix, elongate the pubic symphysis and
inhibit uterine contraction. It may have additional roles in
enhancing sperm motility, regulating blood pressure, controlling
heart rate and releasing oxytocin and vasopressin. There are two
alternatively spliced transcript variants encoding different
isoforms described for this gene.
Background References:
- Davila, S., et al. Genes Immun. 11(3):232-238(2010)
- Vogel, I., et al. In Vivo 23(6):1005-1009(2009)
- Dschietzig, T., et al. Regul. Pept. 155 (1-3), 163-173 (2009) :
- Mookerjee, I., et al. FASEB J. 23(4):1219-1229(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This RLN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 139-165 amino acids from the C-terminal region of human RLN2.
NCBI Gene ID #:
6019
NCBI Official Name:
Prorelaxin H2
NCBI Official Symbol:
RLN2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
21 kDa
Protein Accession #:
P04090
Protein GI Number:
132281
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience,Signal Transduction
Swissprot #:
P04090
User NOte:
Optimal dilutions for each application to be determined by the researcher.