STX4 Antibody

ProSci
Product Code: PSI-60-146
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-60-146-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in MDA-MB231 cell line lysates (35ug/lane).

Western blot analysis in MDA-MB231 cell line lysates (35ug/lane).

Further Information

Additional Names:
Syntaxin-4, Renal carcinoma antigen NY-REN-31, STX4, STX4A
Application Note:
For WB starting dilution is: 1:1000
Background:
Plasma membrane t-SNARE that mediates docking of transport vesicles. Necessary for the translocation of SLC2A4 from intracellular vesicles to the plasma membrane. Together with STXB3 and VAMP2, may also play a role in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes (By similarity). May also play a role in docking of synaptic vesicles at presynaptic active zones.
Background References:
  • Evesson, F.J., et al. J. Biol. Chem. 285(37):28529-28539(2010)
  • Kennedy, M.J., et al. Cell 141(3):524-535(2010)
  • Brochetta, C., et al. Biochim. Biophys. Acta 1783(10):1781-1791(2008)
  • Cooper, G.M., et al. Blood 112(4):1022-1027(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat
Immunogen:
This STX4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 132-160 amino acids from the Central region of human STX4.
NCBI Gene ID #:
6810
NCBI Official Name:
Syntaxin-4
NCBI Official Symbol:
STX4
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
34 kDa
Protein Accession #:
Q12846
Protein GI Number:
3041737
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience,Signal Transduction
Swissprot #:
Q12846
User NOte:
Optimal dilutions for each application to be determined by the researcher.