KCNIP2 Antibody
Code | Size | Price |
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PSI-60-491-400ul | 400ul | £626.00 |
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Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
Kv channel-interacting protein 2, KChIP2, A-type potassium channel modulatory protein 2, Cardiac voltage-gated potassium channel modulatory subunit, Potassium channel-interacting protein 2, KCNIP2, KCHIP2
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a member of the family of voltage-gated
potassium (Kv) channel-interacting proteins (KCNIPs), which belongs
to the recoverin branch of the EF-hand superfamily. Members of the
KCNIP family are small calcium binding proteins. They all have
EF-hand-like domains, and differ from each other in the N-terminus.
They are integral subunit components of native Kv4 channel
complexes. They may regulate A-type currents, and hence neuronal
excitability, in response to changes in intracellular calcium.
Multiple alternatively spliced transcript variants encoding
distinct isoforms have been identified from this gene. [provided by
RefSeq].
Background References:
- Foeger, N.C., et al. J. Biol. Chem. 285(43):33413-33422(2010)
- Lundby, A., et al. Br. J. Pharmacol. 160(8):2028-2044(2010)
- Levy, D.I., et al. J. Physiol. (Lond.) 588 (PT 14), 2657-2668 (2010) :
- Cotella, D., et al. Pflugers Arch. 460(1):87-97(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This KCNIP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 50-78 amino acids from the N-terminal region of human KCNIP2.
NCBI Gene ID #:
30819
NCBI Official Name:
Kv channel-interacting protein 2
NCBI Official Symbol:
KCNIP2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
31 kDa
Protein Accession #:
Q9NS61
Protein GI Number:
338817979
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience,Signal Transduction
Swissprot #:
Q9NS61
User NOte:
Optimal dilutions for each application to be determined by the researcher.