IQCB1 Antibody
| Code | Size | Price |
|---|
| PSI-58-917-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
IQ calmodulin-binding motif-containing protein 1, Nephrocystin-5, p53 and DNA damage-regulated IQ motif protein, PIQ, IQCB1, KIAA0036, NPHP5
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a nephrocystin protein that interacts
with calmodulin and the retinitis pigmentosa GTPase regulator
protein. The encoded protein has a central coiled-coil region and
two calmodulin-binding IQ domains. It is localized to the primary
cilia of renal epithelial cells and connecting cilia of
photoreceptor cells. The protein is thought to play a role in
ciliary function. Defects in this gene result in Senior-Loken
syndrome type 5. Alternative splicing results in multiple
transcript variants.
Background References:
- Hildebrandt, F., et al. J. Am. Soc. Nephrol. 20(1):23-35(2009)
- Schafer, T., et al. Hum. Mol. Genet. 17(23):3655-3662(2008)
- Luo, X., et al. Cancer Res. 65(23):10725-10733(2005)
- le Maire, A., et al. Proteins 59(2):347-355(2005)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This IQCB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 384-411 amino acids from the Central region of human IQCB1.
NCBI Gene ID #:
9657
NCBI Official Name:
IQ calmodulin-binding motif-containing protein 1
NCBI Official Symbol:
IQCB1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
69 kDa
Protein Accession #:
Q15051
Protein GI Number:
3123054
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience,Signal Transduction
Swissprot #:
Q15051
User NOte:
Optimal dilutions for each application to be determined by the researcher.