PLEKHG5 Antibody

ProSci
Product Code: PSI-59-089
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-59-089-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in A549 cell line lysates (35ug/lane).

Western blot analysis in A549 cell line lysates (35ug/lane).

Further Information

Additional Names:
Pleckstrin homology domain-containing family G member 5, PH domain-containing family G member 5, Guanine nucleotide exchange factor 720, GEF720, PLEKHG5, KIAA0720
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a protein that activates the nuclear factor kappa B (NFKB1) signaling pathway. Multations in this gene have been found in a family with distal spinal muscular atrophy.
Background References:
  • Hosgood, H.D. III, et al. Occup Environ Med 66(12):848-853(2009)
  • Newton-Cheh, C., et al. Nat. Genet. 41(4):399-406(2009)
  • Maystadt, I., et al. Am. J. Hum. Genet. 81(1):67-76(2007)
  • Rabizadeh, S., et al. Cytokine Growth Factor Rev. 14 (3-4), 225-239 (2003) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Immunogen:
This PLEKHG5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 175-202 amino acids from the N-terminal region of human PLEKHG5.
NCBI Gene ID #:
57449
NCBI Official Name:
Pleckstrin homology domain-containing family G member 5
NCBI Official Symbol:
PLEKHG5
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
117 kDa
Protein Accession #:
O94827
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience,Signal Transduction
Swissprot #:
O94827
User NOte:
Optimal dilutions for each application to be determined by the researcher.