TRPC4 Antibody
| Code | Size | Price |
|---|
| PSI-58-703-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Short transient receptor potential channel 4, TrpC4, Trp-related protein 4, hTrp-4, hTrp4, TRPC4
Application Note:
For WB starting dilution is: 1:1000
Background:
Form a receptor-activated non-selective calcium permeant cation channel. Acts as a cell-cell contact-dependent endothelial calcium entry channel. Probably operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Mediates cation entry, with an enhanced permeability to barium over calcium. May also be activated by intracellular calcium store depletion.
Background References:
- Mace, K.E., et al. J. Cell. Physiol. 225(2):444-453(2010)
- von Spiczak, S., et al. Neuromolecular Med. 12(3):292-299(2010)
- Pinheiro, A.P., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 153B (5), 1070-1080 (2010) :
- Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine
Immunogen:
This TRPC4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 812-840 amino acids from the C-terminal region of human TRPC4.
NCBI Gene ID #:
7223
NCBI Official Name:
Short transient receptor potential channel 4
NCBI Official Symbol:
TRPC4
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
112 kDa
Protein Accession #:
Q9UBN4
Protein GI Number:
13633994
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience,Signal Transduction
Swissprot #:
Q9UBN4
User NOte:
Optimal dilutions for each application to be determined by the researcher.