LIM2 Antibody

ProSci
Product Code: PSI-58-347
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-58-347-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in MDA-MB453 cell line lysates (35ug/lane).

Western blot analysis in MDA-MB453 cell line lysates (35ug/lane).

Further Information

Additional Names:
Lens fiber membrane intrinsic protein, MP18, MP19, MP20, LIM2
Application Note:
For WB starting dilution is: 1:1000
Background:
LIM2 is an eye lens-specific protein found at the junctions of lens fiber cells, where it may contribute to cell junctional organization. It acts as a receptor for calmodulin, and may play an important role in both lens development and cataractogenesis. Mutations in this gene have been associated with cataract formation.
Background References:
  • Ponnam, S.P., et al. Mol. Vis. 14, 1204-1208 (2008) :
  • Hsu, H., et al. Sheng Wu Gong Cheng Xue Bao 20(4):507-515(2004)
  • Wistow, G., et al. Mol. Vis. 8, 171-184 (2002) :
  • Wistow, G., et al. Mol. Vis. 8, 185-195 (2002) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat
Immunogen:
This LIM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 110-137 amino acids from the C-terminal region of human LIM2.
NCBI Gene ID #:
3982
NCBI Official Name:
Lens fiber membrane intrinsic protein
NCBI Official Symbol:
LIM2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
20 kDa
Protein Accession #:
P55344
Protein GI Number:
17433717
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience,Signal Transduction
Swissprot #:
P55344
User NOte:
Optimal dilutions for each application to be determined by the researcher.