DNAI1 Antibody
| Code | Size | Price |
|---|
| PSI-58-705-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Dynein intermediate chain 1, axonemal, Axonemal dynein intermediate chain 1, DNAI1
Application Note:
For WB starting dilution is: 1:1000
Background:
The inner- and outer-arm dyneins, which bridge between the
doublet microtubules in axonemes, are the force-generating proteins
responsible for the sliding movement in axonemes. The intermediate
and light chains, thought to form the base of the dynein arm, help
mediate attachment and may also participate in regulating dynein
activity. This gene encodes an intermediate chain dynein, belonging
to the large family of motor proteins. Mutations in this gene
result in abnormal ciliary ultrastructure and function associated
with primary ciliary dyskinesia (PCD) and Kartagener syndrome.
Background References:
- Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
- Leigh, M.W., et al. Curr. Opin. Pediatr. 21(3):320-325(2009)
- Zuccarello, D., et al. Hum. Reprod. 23(8):1957-1962(2008)
- Failly, M., et al. Respiration 76(2):198-204(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat
Immunogen:
This DNAI1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 92-120 amino acids from the N-terminal region of human DNAI1.
NCBI Gene ID #:
27019
NCBI Official Name:
Dynein intermediate chain 1, axonemal
NCBI Official Symbol:
DNAI1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
79 kDa
Protein Accession #:
Q9UI46
Protein GI Number:
12643888
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience,Signal Transduction
Swissprot #:
Q9UI46
User NOte:
Optimal dilutions for each application to be determined by the researcher.