P2RX6 Antibody
| Code | Size | Price |
|---|
| PSI-58-955-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
P2X purinoceptor 6, P2X6, ATP receptor, P2XM, Purinergic receptor, Purinergic receptor P2X-like 1, P2RX6, P2RXL1, P2X6
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene belongs to the family of
P2X receptors, which are ATP-gated ion channels and mediate rapid
and selective permeability to cations. This gene is predominantly
expressed in skeletal muscle, and regulated by p53. The encoded
protein is associated with VE-cadherin at the adherens junctions of
human umbilical vein endothelial cells. Alternative splicing
results in multiple transcript variants. A related pseudogene,
which is also located on chromosome 22, has been identified.
Background References:
- Trynka, G., et al. Gut 58(8):1078-1083(2009)
- Luke, M.M., et al. Stroke 40(2):363-368(2009)
- Palomino-Doza, J., et al. Hypertension 52(5):980-985(2008)
- Shiffman, D., et al. Arterioscler. Thromb. Vasc. Biol. 28(1):173-179(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This P2RX6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 198-226 amino acids from the Central region of human P2RX6.
NCBI Gene ID #:
9127
NCBI Official Name:
P2X purinoceptor 6
NCBI Official Symbol:
P2RX6
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
49 kDa
Protein Accession #:
O15547
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience,Signal Transduction
Swissprot #:
O15547
User NOte:
Optimal dilutions for each application to be determined by the researcher.