PCDH17 Antibody

ProSci
Product Code: PSI-64-140
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-64-140-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Flow Cytometry
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis of PCDH17 Antibody in 293 cell line lysates (35ug/lane)
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Flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Western blot analysis of PCDH17 Antibody in 293 cell line lysates (35ug/lane)
Flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Further Information

Additional Names:
Protocadherin-17, Protocadherin-68, PCDH17, PCDH68, PCH68
Application Note:
For WB starting dilution is: 1:1000

For FACS starting dilution is: 1:10~50
Background:
This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The encoded protein contains six extracellular cadherin domains, a transmembrane domain, and a cytoplasmic tail differing from those of the classical cadherins. The encoded protein may play a role in the establishment and function of specific cell-cell connections in the brain.
Background References:
  • Biswas, S., et al. Dev. Genes Evol. 219(5):265-271(2009)
  • Charles, C.A., et al. J. Am. Acad. Dermatol. 59(5):758-771(2008)
  • Sherwin, J.R., et al. Hum. Reprod. 23(5):1063-1068(2008)
  • Abrahams, B.S., et al. Proc. Natl. Acad. Sci. U.S.A. 104(45):17849-17854(2007)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This PCDH17 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1107-1136 amino acids from the C-terminal region of human PCDH17.
NCBI Gene ID #:
27253
NCBI Official Name:
Protocadherin-17
NCBI Official Symbol:
PCDH17
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
126 kDa
Protein Accession #:
O14917
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience,Signal Transduction
Swissprot #:
O14917
User NOte:
Optimal dilutions for each application to be determined by the researcher.