CACNA2D4 Antibody
| Code | Size | Price |
|---|
| PSI-62-014-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Flow Cytometry
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Voltage-dependent calcium channel subunit alpha-2/delta-4, Voltage-gated calcium channel subunit alpha-2/delta-4, Voltage-dependent calcium channel subunit alpha-2-4, Voltage-dependent calcium channel subunit delta-4, CACNA2D4
Application Note:
For WB starting dilution is: 1:1000
For FACS starting dilution is: 1:10~50
For FACS starting dilution is: 1:10~50
Background:
CACNA2D4 is a member of the alpha-2/delta subunit
family, a protein in the voltage-dependent calcium channel complex.
Calcium channels mediate the influx of calcium ions into the cell
upon membrane polarization and consist of a complex of alpha-1,
alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various
versions of each of these subunits exist, either expressed from
similar genes or the result of alternative splicing. Research on a
highly similar protein in rabbit suggests the protein described in
this record is cleaved into alpha-2 and delta subunits. Alternate
transcriptional splice variants of this gene have been observed but
have not been thoroughly characterized.
Background References:
- Wycisk, K.A., et al. Am. J. Hum. Genet. 79(5):973-977(2006)
- Qin, N., et al. Mol. Pharmacol. 62(3):485-496(2002)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This CACNA2D4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 89-118 amino acids from the N-terminal region of human CACNA2D4.
NCBI Gene ID #:
93589
NCBI Official Name:
Voltage-dependent calcium channel subunit alpha-2/delta-4
NCBI Official Symbol:
CACNA2D4
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
128 kDa
Protein Accession #:
Q7Z3S7
Protein GI Number:
296434419
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience,Signal Transduction
Swissprot #:
Q7Z3S7
User NOte:
Optimal dilutions for each application to be determined by the researcher.