PMAT Antibody
| Code | Size | Price |
|---|
| PSI-55-485-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Equilibrative nucleoside transporter 4, Solute carrier family 29 member 4, Slc29a4, Ent4
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Background:
PMAT(Slc29a4) is a member of the SLC29 family. It is a plasma membrane protein with 11 transmembrane helices. This protein catalyzes the reuptake of monoamines into presynaptic neurons, thus determining the intensity and duration of monoamine neural signaling. It has been shown to transport several compounds, including serotonin, dopamine, and the neurotoxin 1-methyl-4-phenylpyridinium.
Background References:
- Barnes,K., Circ. Res. 99 (5), 510-519 (2006)
- Engel,K., J. Biol. Chem. 279 (48), 50042-50049 (2004)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This PMAT(Slc29a4) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 39-69 amino acids from the N-terminal region of human PMAT(Slc29a4).
NCBI Gene ID #:
243328
NCBI Official Name:
Equilibrative nucleoside transporter 4
NCBI Official Symbol:
Slc29a4
NCBI Organism:
Mus musculus
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
58 kDa
Protein Accession #:
Q8R139
Purification:
This antibody is purified through a protein G column, followed by dialysis against PBS.
Research Area:
Neuroscience,Signal Transduction
Swissprot #:
Q8R139
User NOte:
Optimal dilutions for each application to be determined by the researcher.