PCPTP1 Antibody
| Code | Size | Price |
|---|
| PSI-63-457-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Receptor-type tyrosine-protein phosphatase R, R-PTP-R, Ch-1PTPase, NC-PTPCOM1, Protein-tyrosine phosphatase PCPTP1, PTPRR, ECPTP, PTPRQ
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Background:
PCPTP1 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domains, and thus represents a receptor-type PTP. The similar gene for this protein predominately expressed in mouse brain was found to associate with, and thus regulate the activity and cellular localization of MAP kinases. The rat counterpart of the gene for this protein was reported to be regulated by the nerve growth factor, which suggested a function in neuronal growth and differentiation.
Background References:
- Blanco-Aparicio, C., et al., J. Cell Biol. 147(6):1129-1136 (1999).
- Ogata, M., et al., J. Biol. Chem. 270(5):2337-2343 (1995).
- Shiozuka, K., et al., Gene 162(2):279-284 (1995).
- Sharma, E., et al., J. Biol. Chem. 270(1):49-53 (1995).
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This PCPTP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 234-265 amino acids from the N-terminal region of human PCPTP1.
NCBI Gene ID #:
5801
NCBI Official Name:
Receptor-type tyrosine-protein phosphatase R
NCBI Official Symbol:
PTPRR
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
74 kDa
Protein Accession #:
Q15256
Protein GI Number:
134039192
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Research Area:
Neuroscience,Signal Transduction
Swissprot #:
Q15256
User NOte:
Optimal dilutions for each application to be determined by the researcher.