STXBP3 Antibody

ProSci
Product Code: PSI-56-447
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-56-447-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in SK-BR-3 cell line lysates (35ug/lane).
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STXBP3 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

Western blot analysis in SK-BR-3 cell line lysates (35ug/lane).
STXBP3 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

Further Information

Additional Names:
Syntaxin-binding protein 3, Platelet Sec1 protein, PSP, Protein unc-18 homolog 3, Unc18-3, Protein unc-18 homolog C, Unc-18C, STXBP3
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50
Background:
Together with STX4 and VAMP2, STXBP3 may play a role in insulin-dependent movement of GLUT4 and in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes (By similarity).
Background References:
  • Bostrom, P., et al. Diabetes 59(8):1870-1878(2010)
  • Ban, H.J., et al. BMC Genet. 11, 26 (2010) :
  • Brochetta, C., et al. Biochim. Biophys. Acta 1783(10):1781-1791(2008)
  • Smithers, N.P., et al. J. Recept. Signal Transduct. Res. 28(6):581-589(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This STXBP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 145-171 amino acids from the Central region of human STXBP3.
NCBI Gene ID #:
6814
NCBI Official Name:
Syntaxin-binding protein 3
NCBI Official Symbol:
STXBP3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
68 kDa
Protein Accession #:
O00186
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience,Signal Transduction
Swissprot #:
O00186
User NOte:
Optimal dilutions for each application to be determined by the researcher.