SFRS7 Antibody
Code | Size | Price |
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PSI-56-336-400ul | 400ul | £626.00 |
Quantity:
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Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
Serine/arginine-rich splicing factor 7, Splicing factor 9G8, Splicing factor, arginine/serine-rich 7, SRSF7, SFRS7
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Background:
The protein encoded by this gene is a member of the
serine/arginine (SR)-rich family of pre-mRNA splicing factors,
which constitute part of the spliceosome. Each of these factors
contains an RNA recognition motif (RRM) for binding RNA and an RS
domain for binding other proteins. The RS domain is rich in serine
and arginine residues and facilitates interaction between different
SR splicing factors. In addition to being critical for mRNA
splicing, the SR proteins have also been shown to be involved in
mRNA export from the nucleus and in translation. Two transcript
variants encoding different isoforms have been found for this gene.
Background References:
- Kimura, T., et al. Med Mol Morphol 43(3):145-157(2010)
- Escudero-Paunetto, L., et al. Virology 401(2):155-164(2010)
- Manley, J.L., et al. Genes Dev. 24(11):1073-1074(2010)
- Valente, S.T., et al. Mol. Cell 36(2):279-289(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse
Immunogen:
This SFRS7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 69-98 amino acids from the N-terminal region of human SFRS7.
NCBI Gene ID #:
6432
NCBI Official Name:
Serine/arginine-rich splicing factor 7
NCBI Official Symbol:
SRSF7
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
27 kDa
Protein Accession #:
Q16629
Protein GI Number:
3929380
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience,Signal Transduction
Swissprot #:
Q16629
User NOte:
Optimal dilutions for each application to be determined by the researcher.