MLPH Antibody
| Code | Size | Price |
|---|
| PSI-56-536-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Melanophilin, Exophilin-3, Slp homolog lacking C2 domains a, SlaC2-a, Synaptotagmin-like protein 2a, MLPH, SLAC2A
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Background:
This gene encodes a member of the exophilin subfamily of
Rab effector proteins. The protein forms a ternary complex with the
small Ras-related GTPase Rab27A in its GTP-bound form and the motor
protein myosin Va. A similar protein complex in mouse functions to
tether pigment-producing organelles called melanosomes to the actin
cytoskeleton in melanocytes, and is required for visible
pigmentation in the hair and skin. A mutation in this gene results
in Griscelli syndrome type 3, which is characterized by a
silver-gray hair color and abnormal pigment distribution in the
hair shaft. Several alternatively spliced transcript variants of
this gene have been described, but the full-length nature of some
of these variants has not been determined.
Background References:
- Park, J.W., et al. J. Med. Genet. 43(7):598-608(2006)
- Seabra, M.C., et al. Traffic 5(6):393-399(2004)
- Fukuda, M., et al. J. Cell. Sci. 117 (PT 4), 583-591 (2004) :
- Lukusa, T., et al. Genet. Couns. 15(3):293-301(2004)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This MLPH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 541-569 amino acids from the C-terminal region of human MLPH.
NCBI Gene ID #:
79083
NCBI Official Name:
Melanophilin
NCBI Official Symbol:
MLPH
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
66 kDa
Protein Accession #:
Q9BV36
Protein GI Number:
32129730
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience,Signal Transduction
Swissprot #:
Q9BV36
User NOte:
Optimal dilutions for each application to be determined by the researcher.