PCDH1 Antibody
Code | Size | Price |
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PSI-56-180-400ul | 400ul | £626.00 |
Quantity:
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Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunofluorescence (IF)
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
Protocadherin-1, Cadherin-like protein 1, Protocadherin-42, PC42, PCDH1
Application Note:
For IHC-P starting dilution is: 1:10~50
For WB starting dilution is: 1:1000
For IF starting dilution is: 1:10~50
For WB starting dilution is: 1:1000
For IF starting dilution is: 1:10~50
Background:
This gene belongs to the protocadherin subfamily within
the cadherin superfamily. The encoded protein is a membrane protein
found at cell-cell boundaries. It is involved in neural cell
adhesion, suggesting a possible role in neuronal development. The
protein includes an extracelllular region, containing 7
cadherin-like domains, a transmembrane region and a C-terminal
cytoplasmic region. Cells expressing the protein showed cell
aggregation activity. Alternative splicing occurs in this gene.
Background References:
- Koppelman, G.H., et al. Am. J. Respir. Crit. Care Med. 180(10):929-935(2009)
- Rush, J., et al. Nat. Biotechnol. 23(1):94-101(2005)
- Ballif, B.A., et al. Mol. Cell Proteomics 3(11):1093-1101(2004)
- Ballif, B.A., et al. Mol. Cell Proteomics 3(11):1093-1101(2004)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This PCDH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 179-206 amino acids from the N-terminal region of human PCDH1.
NCBI Gene ID #:
5097
NCBI Official Name:
Protocadherin-1
NCBI Official Symbol:
PCDH1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
115 kDa
Protein Accession #:
Q08174
Protein GI Number:
215273864
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience,Signal Transduction
Swissprot #:
Q08174
User NOte:
Optimal dilutions for each application to be determined by the researcher.