P2RY1 Antibody
| Code | Size | Price |
|---|
| PSI-57-841-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
P2Y purinoceptor 1, P2Y1, ATP receptor, Purinergic receptor, P2RY1
Application Note:
For WB starting dilution is: 1:1000
Background:
The product of this gene belongs to the family of
G-protein coupled receptors. This family has several receptor
subtypes with different pharmacological selectivity, which overlaps
in some cases, for various adenosine and uridine nucleotides. This
receptor functions as a receptor for extracellular ATP and ADP. In
platelets binding to ADP leads to mobilization of intracellular
calcium ions via activation of phospholipase C, a change in
platelet shape, and probably to platelet aggregation. [provided by
RefSeq].
Background References:
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Maloney, S.F., et al. Integr Biol (Camb) 2(4):183-192(2010)
- Nisar, S., et al. Traffic 11(4):508-519(2010)
- Kumar, T.S., et al. J. Med. Chem. 53(6):2562-2576(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Chicken, Rat
Immunogen:
This P2RY1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 231-260 amino acids from the Central region of human P2RY1.
NCBI Gene ID #:
5028
NCBI Official Name:
P2Y purinoceptor 1
NCBI Official Symbol:
P2RY1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
42 kDa
Protein Accession #:
P47900
Protein GI Number:
1352692
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience,Signal Transduction,Growth Factor
Swissprot #:
P47900
User NOte:
Optimal dilutions for each application to be determined by the researcher.