SSTR5 Antibody
| Code | Size | Price |
|---|
| PSI-60-259-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Somatostatin receptor type 5, SS-5-R, SS5-R, SS5R, SSTR5
Application Note:
For WB starting dilution is: 1:1000
Background:
Somatostatin and its related peptide cortistatin exert
multiple biological actions on normal and tumoral tissue targets by
interacting with somatostatin receptors (SSTRs). The protein
encoded by this gene is one of the SSTRs, which is a multi-pass
membrane protein and belongs to the G-protein coupled receptor 1
family. The activity of this receptor is mediated by G proteins
which inhibit adenylyl cyclase, and different regions of this
receptor molecule are required for the activation of different
signaling pathways. A mutation in this gene results in somatostatin
analog resistance. Alternatively spliced transcript variants have
been identified in this gene.
Background References:
- Canzian, F., et al. Hum. Mol. Genet. 19(19):3873-3884(2010)
- Saus, E., et al.Psychiatr Res 44(14):971-978(2010)
- Pinheiro, A.P., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 153B (5), 1070-1080 (2010) :
- Duran-Prado, M., et al. J. Clin. Endocrinol. Metab. 95(5):2497-2502(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This SSTR5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 311-339 amino acids from the C-terminal region of human SSTR5.
NCBI Gene ID #:
6755
NCBI Official Name:
Somatostatin receptor type 5
NCBI Official Symbol:
SSTR5
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
39 kDa
Protein Accession #:
P35346
Protein GI Number:
12644225
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience,Signal Transduction,Growth Factor
Swissprot #:
P35346
User NOte:
Optimal dilutions for each application to be determined by the researcher.