S1PR5 Antibody
| Code | Size | Price |
|---|
| PSI-57-714-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Sphingosine 1-phosphate receptor 5, S1P receptor 5, S1P5, Endothelial differentiation G-protein-coupled receptor 8, Sphingosine 1-phosphate receptor Edg-8, S1P receptor Edg-8, S1PR5, EDG8
Application Note:
For WB starting dilution is: 1:1000
Background:
The lysosphingolipid sphingosine 1-phosphate (S1P)
regulates cell proliferation, apoptosis, motility, and neurite
retraction. Its actions may be both intracellular as a second
messenger and extracellular as a receptor ligand. S1P and the
structurally related lysolipid mediator lysophosphatidic acid (LPA)
signal cells through a set of G protein-coupled receptors known as
EDG receptors. Some EDG receptors (e.g., EDG1; MIM 601974) are S1P
receptors; others (e.g., EDG2; MIM 602282) are LPA
receptors.
Background References:
- Chang, C.L., et al. Am. J. Physiol., Cell Physiol. 297 (2), C451-C458 (2009) :
- Gillies, L., et al. Cell. Signal. 21(5):675-684(2009)
- Miron, V.E., et al. Ann. Neurol. 63(1):61-71(2008)
- Ulfig, N., et al. Acta Histochem. 106(5):373-378(2004)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This S1PR5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 219-247 amino acids from the Central region of human S1PR5.
NCBI Gene ID #:
53637
NCBI Official Name:
Sphingosine 1-phosphate receptor 5
NCBI Official Symbol:
S1PR5
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
42 kDa
Protein Accession #:
Q9H228
Protein GI Number:
62510663
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience,Signal Transduction,Growth Factor
Swissprot #:
Q9H228
User NOte:
Optimal dilutions for each application to be determined by the researcher.