AVPR1B Antibody
| Code | Size | Price |
|---|
| PSI-57-446-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Vasopressin V1b receptor, V1bR, AVPR V1b, AVPR V3, Antidiuretic hormone receptor 1b, Vasopressin V3 receptor, AVPR1B, AVPR3, VPR3
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene acts as receptor for
arginine vasopressin. This receptor belongs to the subfamily of
G-protein coupled receptors which includes AVPR1A, V2R and OXT
receptors. Its activity is mediated by G proteins which stimulate a
phosphatidylinositol-calcium second messenger system. The receptor
is primarily located in the anterior pituitary, where it stimulates
ACTH release. It is expressed at high levels in ACTH-secreting
pituitary adenomas as well as in bronchial carcinoids responsible
for the ectopic ACTH syndrome. A spliced antisense transcript of
this gene has been reported but its function is not known.
Background References:
- van West, D., et al. Psychiatry Res 179(1):64-68(2010)
- Binder, E.B., et al. Arch. Gen. Psychiatry 67(4):369-379(2010)
- Bosker, F.J., et al. Mol. Psychiatry (2010) In press :
- van West, D., et al. Psychiatr. Genet. 19(2):102-103(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This AVPR1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 289-317 amino acids from the C-terminal region of human AVPR1B.
NCBI Gene ID #:
553
NCBI Official Name:
Vasopressin V1b receptor
NCBI Official Symbol:
AVPR1B
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
47 kDa
Protein Accession #:
P47901
Protein GI Number:
1351392
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience,Signal Transduction,Growth Factor
Swissprot #:
P47901
User NOte:
Optimal dilutions for each application to be determined by the researcher.