EIF4EBP2 Antibody

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ProSci
Product Code: PSI-60-797
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-60-797-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis of lysate from human brain tissue lysate, using EIF4EBP2 Antibody at 1:1000 at each lane.
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Western blot analysis of lysate from human brain tissue lysate, using EIF4EBP2 Antibody at 1:1000 at each lane.

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Further Information

Additional Names:
Eukaryotic translation initiation factor 4E-binding protein 2, 4E-BP2, eIF4E-binding protein 2, EIF4EBP2
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a member of the eukaryotic translation initiation factor 4E binding protein family. The gene products of this family bind eIF4E and inhibit translation initiation. However, insulin and other growth factors can release this inhibition via a phosphorylation-dependent disruption of their binding to eIF4E. Regulation of protein production through these gene products have been implicated in cell proliferation, cell differentiation and viral infection.
Background References:
  • Bailey, S.D., et al. Diabetes Care (2010) In press :
  • Bidinosti, M., et al. J. Biol. Chem. 285(25):19402-19408(2010)
  • Johnatty, S.E., et al. PLoS Genet.(7), E1001016 (2010) :
  • Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This EIF4EBP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 87-115 amino acids from the C-terminal region of human EIF4EBP2.
NCBI Gene ID #:
1979
NCBI Official Name:
Eukaryotic translation initiation factor 4E-binding protein 2
NCBI Official Symbol:
EIF4EBP2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
13 kDa
Protein Accession #:
Q13542
Protein GI Number:
34921510
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity
Swissprot #:
Q13542
User NOte:
Optimal dilutions for each application to be determined by the researcher.