NRF1 Antibody
| Code | Size | Price |
|---|
| PSI-57-796-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Nuclear respiratory factor 1, NRF-1, Alpha palindromic-binding protein, Alpha-pal, NRF1
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a protein that homodimerizes and
functions as a transcription factor which activates the expression
of some key metabolic genes regulating cellular growth and nuclear
genes required for respiration, heme biosynthesis, and
mitochondrial DNA transcription and replication. The protein has
also been associated with the regulation of neurite outgrowth.
Alternate transcriptional splice variants, which encode the same
protein, have been characterized. Additional variants encoding
different protein isoforms have been described but they have not
been fully characterized. Confusion has occurred in bibliographic
databases due to the shared symbol of NRF1 for this gene and for
'nuclear factor (erythroid-derived 2)-like 1' which has an official
symbol of NFE2L1.
Background References:
- Gonen, N., et al. J. Biol. Chem. 285(44):33602-33613(2010)
- Zhang, Y., et al. Biochem. J. 430(3):497-510(2010)
- Shao, D., et al. Mitochondrion 10(5):516-527(2010)
- Adam, T., et al. Biochem. Biophys. Res. Commun. 398(3):495-499(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Zebrafish, Mouse
Immunogen:
This NRF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 226-255 amino acids from the Central region of human NRF1.
NCBI Gene ID #:
4899
NCBI Official Name:
Nuclear respiratory factor 1
NCBI Official Symbol:
NRF1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
54 kDa
Protein Accession #:
Q16656
Protein GI Number:
12643732
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity
Swissprot #:
Q16656
User NOte:
Optimal dilutions for each application to be determined by the researcher.