MRPS11 Antibody
| Code | Size | Price |
|---|
| PSI-59-285-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
28S ribosomal protein S11, mitochondrial, MRP-S11, S11mt, Cervical cancer proto-oncogene 2 protein, HCC-2, MRPS11, RPMS11
Application Note:
For WB starting dilution is: 1:1000
Background:
Mammalian mitochondrial ribosomal proteins are encoded by
nuclear genes and help in protein synthesis within the
mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a
small 28S subunit and a large 39S subunit. They have an estimated
75% protein to rRNA composition compared to prokaryotic ribosomes,
where this ratio is reversed. Another difference between mammalian
mitoribosomes and prokaryotic ribosomes is that the latter contain
a 5S rRNA. Among different species, the proteins comprising the
mitoribosome differ greatly in sequence, and sometimes in
biochemical properties, which prevents easy recognition by sequence
homology. This gene encodes a 28S subunit protein that contains a
high level of sequence similarity with ribosomal protein S11P
family members. A pseudogene corresponding to this gene is found on
chromosome 20. Sequence analysis identified two transcript variants
that encode different protein isoforms.
Background References:
- Ishiguchi, H., et al. Int. J. Cancer 111(6):900-909(2004)
- Zhang, Z., et al. Genomics 81(5):468-480(2003)
- Kenmochi, N., et al. Genomics 77 (1-2), 65-70 (2001) :
- Suzuki, T., et al. J. Biol. Chem. 276(35):33181-33195(2001)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This MRPS11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 42-69 amino acids from the Central region of human MRPS11.
NCBI Gene ID #:
64963
NCBI Official Name:
28S ribosomal protein S11, mitochondrial
NCBI Official Symbol:
MRPS11
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
21 kDa
Protein Accession #:
P82912
Protein GI Number:
21263985
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Obesity
Swissprot #:
P82912
User NOte:
Optimal dilutions for each application to be determined by the researcher.